Kyle J. Norton
Carrots may have a profound and positive effect in reduced over expression reactive oxygen species that cause chronic diseases, through antioxidant activities, some scientists suggested.
Antioxidant is a substance characterized by its function in inhibited oxidation, especially in balanced the ratio of free radicals and antioxidant levels in the body to prevent the initiation of oxidatively related diseases.
Chronic diseases are conditions that last longer than 3 months and can not cure by medication.
The diseases are most common in aging population.
Most common chronic diseases are arthritis, cardiovascular disease such as heart attacks and stroke. Cancer such as breast and colon cancer, diabetes.
The efficacy of carrot acted as an antioxidant to protect against oxidation was reported by numbers of institution including the Texas A&M University and University of Messina.
According to the investigation of phenolic antioxidants in three carrots cultivars (Navajo, Legend and Choctaw) were studied under different wounding intensities (A/W) during storage, researchers found that carrot soluble phenolics exert a significant antioxidant capacity (AOX), and PAL activity in protect against increased with A/W for all cultivars.
In Intense wounding (23.5 cm(2)/g) induced an ∼2.5- and ∼12.4-fold displayed a strong in increased production of soluble phenolics and AOX, respectively, after 4 days in compared to whole and lesser wound carrots through the AOX synthesis of mainly chlorogenic acid (5-CQA) and 3,5-dicaffeoylquinic acid.
These results suggested that intentional carrot wound may have a potential effect as an inexpensive rich source of phenolic antioxidants for the regular diet (with some resistances from public), as Dr. Surjadinata BB, the lead author said, ” By simply increasing wounding stress intensity it is possible to enhance the biosynthesis of phenolic antioxidants”.
Black carrot (Daucus carota L. ssp. sativus var. atrorubens Alef.) is a valuable source of carbohydrates, minerals and vitamins.
The root vegetable contains also high amounts of anthocyanins in expression of the characteristic of deep-purple color.
Furthermore, BCCE exhibited a strong anti-angiogenic activity against free radical in alternated DNA of healthy cells in initiation of tumor proliferation, at the highest concentration assayed on the chick chorioallantoic membrane (50μg/egg).
Interestingly, ingestion of black carrot crude extract (BCCE) also promoted cytoprotective effect against ROS in causing healthy cell damage and apoptosis.
After taking account of other con founders and re-examine the final results, Dr.Olejnik A, the lead scientist said, “PC extract is capable of colonic cells’ protection against the adverse effects of oxidative stress”.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it’s news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Biosynthesis of phenolic antioxidants in carrot tissue increases with wounding intensity by Surjadinata BB1, Cisneros-Zevallos L.(PubMed)
(2) Polyphenolic profile and biological activities of black carrot crude extract (Daucus carota L. ssp. sativus var. atrorubens Alef.) by Smeriglio A1, Denaro M1, Barreca D1, D’Angelo V1, Germanò MP2, Trombetta D1.(PubMed)
(3) Antioxidant effects of gastrointestinal digested purple carrot extract on the human cells of colonic mucosa by Olejnik A1, Rychlik J2, Kidoń M3, Czapski J3, Kowalska K2, Juzwa W2, Olkowicz M2, Dembczyński R2, Moyer MP4.(PubMed)
(4) The Burden of Chronic Disease: The Future is Prevention Introduction to Dr. James Marks’ presentation, “The Burden of Chronic Disease and the Future of Public Health” by George E. Hardy, Jr., MD, MPH, Executive Director(PMC)